Two component reaction for the synthesis of Quinolines in the presence of γ-Al2O3 and Cu/ZnO nanoparticles

Document Type : Short Communication


1 Department of biology, Garmsar branch, Islamic Azad University, Garmsar, Iran.

2 Polymer Research Laboratory, University of Bonab, Bonab, I. R. Iran.

3 Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran.

4 Department of Basic Sciences, Sari Agricultural Sciences and Natural Resources University, P.O. Box 578, Sari 4818168984, Iran.



Two-component reaction of 2-aminobenzophenones with acetylenic esters in the presence of γ-Al2O3 and Cu/ZnO as suitable heterogeneous catalysts has been studied. Nano γ-Al2O3 and Cu/ZnO showed high activities when used as surface catalysts for the synthesis of quinoline derivatives. After completion of the reaction, the catalyst was recovered and reused several times under the same reaction conditions.