Chemical synthesis of Zinc Oxide (ZnO) nanoparticles and their antibacterial activity against a clinical isolate Staphylococcus aureus

Document Type : Reasearch Paper


Applied Microbiology Laboratory, Department of Virology, Sri Venkateswara University, Tirupati-517502 Andhra Pradesh, India.



In this study, Zinc Oxide nanoparticles (ZnONPs) were synthesized by chemical method and their antibacterial efficiency against a clinical isolate of Staphylococcus aureus was studied. The Zinc Oxide nanoparticles have shown a commendable inhibition effect on the growth of most notorious bacterial pathogen S.aureus. The nanoparticles size and shapes were characterized by transmission electron microscopy (TEM). The rod shaped zinc nanoparticles were formed as as a result of fast reduction rate of the precursor.  The shape controlled nanocrystals possess well defined surfaces and morphologies and showed an excellent antibacterial property against clinical bacterial strain S. aureus.